Amino-PEG5-t-butyl ester
- Product Name
- Amino-PEG5-t-butyl ester
- CAS No.
- 1446282-18-3
- Chemical Name
- Amino-PEG5-t-butyl ester
- Synonyms
- Amino-PEG5-Boc;Amino-PEG5-COOtBu;NH2-PEG5-C2-COOtBu;NH2-PEG5-CH2CH2COOtBu;H2N-PEG5-CH2CH2COOtBu;Amino-PEG5-t-Bu Ester;Amino-PEG5-t-butyl este;Amino-PEG5-t-butyl ester;tert-butyl 1-amino-3,6,9,12,15-pentaoxaoctadecan-18-oate;4,7,10,13,16-Pentaoxaoctadecanoic acid, 18-amino-, 1,1-dimethylethyl ester
- CBNumber
- CB23048678
- Molecular Formula
- C17H35NO7
- Formula Weight
- 365.46
- MOL File
- 1446282-18-3.mol
Amino-PEG5-t-butyl ester Property
- Boiling point:
- 439.1±40.0 °C(Predicted)
- Density
- 1.049±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 8.74±0.10(Predicted)
- form
- viscous liquid
- color
- Light yellowish
Safety
- HS Code
- 2942000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- A615295
- Product name
- Amino-PEG5-t-butylester
- Packaging
- 25mg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- A615295
- Product name
- Amino-PEG5-t-butylester
- Packaging
- 100mg
- Price
- $450
- Updated
- 2021/12/16
- Product number
- AS103925
- Product name
- H2N-PEG5-CH2CH2COOtBu
- Purity
- 95+%
- Packaging
- 1g
- Price
- $421
- Updated
- 2021/12/16
- Product number
- BP-21698
- Product name
- Amino-PEG5-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $290
- Updated
- 2021/12/16
- Product number
- 0456DY
- Product name
- Amino-PEG5-t-butylester
- Packaging
- 1g
- Price
- $789
- Updated
- 2021/12/16
Amino-PEG5-t-butyl ester Chemical Properties,Usage,Production
Description
Amino-PEG5-t-butyl ester is a PEG molecule consisting of an amino group and a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG5-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
Amino-PEG5-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Amino-PEG5-t-butyl ester Suppliers
View Lastest Price from Amino-PEG5-t-butyl ester manufacturers
- Product
- Amino-PEG5-COOtBu 1446282-18-3
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-22